—–Iyi ngingo yakuwe muriMedpage Uyu munsi
Kurandura intanga zombi mbere yo gucura bifitanye isano n’uko bishoboka cyane ko ibibazo by’ubuzima bidakira ndetse no kugabanya imikorere y’umubiri nyuma yimyaka, cyane cyane ku bagore babazwe mbere, ubushakashatsi bwakozwe bwerekanye ko.
Ugereranije n'itsinda rihuje n'imyaka, abagore bari munsi yimyaka 46 babazwe oophorectomy (PBO) mbere yo gucura (PBO) kubihe bidasanzwe-hamwe na hysterectomie-bitakozwe neza cyane mugupimisha urugendo rw'iminota itandatu rwakorewe mubitaro by’ubuvuzi nyuma yimyaka 20 kandi birashoboka cyane. kugira ibihe bidakira:
Asima: cyangwa 1.74 (95% CI 1.03-2.93)
Indwara ya rubagimpande: cyangwa 1.64 (95% CI 1.06-2.55)
Kubuza gusinzira apnea: cyangwa 2.00 (95% CI 1.23-3.26)
Kuvunika: cyangwa 2.86 (95% CI 1.17-6.98)
Abashakashatsi bayobowe na Michelle Mielke, MD, PhD, wo mu ishuri rya kaminuza ya Wake Forest School, yagize ati: Ubuvuzi muri Winston-Salem, NC, mu kiganiro muri Menopause.Ibisubizo nibyingenzi mugihe usuzumye niba ugomba gukorerwa ovariectomy (PBO) na hysterectomy.
Stephanie Faubion, MD, MBA, umuyobozi w’ubuvuzi w’umuryango wa Menopause, yavuze ko ibyavuye mu bushakashatsi bishingiye ku gitabo cyitwa Mayo Clinic's Tubectomy na Aging Cohort Study-2 (MOA-2), byemeza ko abaganga bagomba guhindura imikorere yabo.
Faubion yatangarije MedPage Today ati: "Ibi byiyongera ku bitabo biriho bivanaho gukuramo intanga ngore, cyane cyane munsi y’imyaka 46, bifitanye isano n’ubuzima bubi."Kuri ubu, ndatekereza ko tugomba gufata ingamba gusa. ”
Faubion, akaba n'umuyobozi w'ikigo cy’ubuzima bw’abagore ku ivuriro rya Mayo i Rochester, muri Leta ya Minnesota, ariko akaba ataragize uruhare muri ubu bushakashatsi, yavuze ko gushyingirwa nyuma (abagore bafite hagati y’imyaka 46 na 49) na byo “atari a igitekerezo cyiza, ”nk'uko ubushakashatsi bubyerekana.Muri iri tsinda, habayeho kwiyongera kwa arthrite na apnea yo gusinzira ugereranije na bagenzi babo bahuje imyaka, kandi PBO yatumye abantu benshi barwara indwara zidakira zifata ibihaha muri cohort yose.
Mu itsinda rya PBO, abagera kuri 90 ku ijana na bo babazwe hysterectomie, naho 6 ku ijana bari bafite hysterectomie mbere yibyo;mu matsinda ahuza imyaka itigeze ikorerwa PBO, 9 ku ijana bari bafite hysterectomy.
Mielke yatangarije MedPage Uyu munsi ko gukuramo intanga ngore mugihe cya hysterectomie (kubagwa bwa kabiri bikunze kugaragara ku bagore) ni ibintu bisanzwe ku bagore, igice kuko bikuraho ibyago byo kurwara kanseri yintanga.
Mielke abisobanura agira ati: “Mu mateka, byizerwaga ko iyo nyababyeyi imaze gukurwaho, itazongera kubaho ubushobozi bwo kororoka, bityo rero ntihazaba hakenewe gukuramo intanga.”Ariko, uko ibihe bigenda bisimburana, ubushakashatsi bwinshi bwerekanye ko gukuramo intanga zombi mbere yo gucura bishobora kugira ingaruka ndende cyangwa ingaruka zigihe kirekire zizindi ndwara.
Amata yavuze ko niba intanga ngabo zavanyweho mbere yo gucura, Milk yavuze ko "ari byiza cyane" ko abagore bakomeza kuvura estrogene kugeza ku myaka 50.
Abashakashatsi bavuze ko ubu bushakashatsi burimo isuzuma ryuzuye ry’umuntu ku bagore bafite amateka yanditse kuri PBO, mu gihe ubundi bushakashatsi bwakozwe kuri PBO n’ibisubizo by’ubuzima bwashingiye ahanini ku gukusanya ibisubizo bivuye mu bitabo by’ubuvuzi, binanirwa gufata “domaine zihariye. y'imikorere y'umubiri cyangwa izindi ngamba zijyanye no gusaza. ”
Ibisobanuro birambuye
Mielke na bagenzi be bakoresheje amakuru yavuye mu mushinga wa Rochester Epidemiology Project (REP) Medical Record Linkage Sisitemu hamwe n’ubushakashatsi bwa MOA-2, bwagaragaje abagore bo mu Ntara ya Olmsted, muri Leta ya Minnesota, bavuwe na PBO kubera ibintu bidasanzwe hagati ya 1988 na 2007 kandi batari bahari ibyago byinshi byo kurwara kanseri yintanga. Abitabiriye MOA-2 bagereranijwe nitsinda ryerekanwe ryabagore batabonye PBO bahujwe nitsinda ryabagore batabonye PBO.
Kugeza mu mwaka wa 2018, igihe ubushakashatsi imbonankubone bwatangiraga, benshi mu bari mu matsinda ya PBO hamwe n’abandi bari bakiriho (91,6% na 93.1%).
Itsinda ry’ubushakashatsi ryashakishije abagore 274 bavuga icyongereza bo muri MOA-2 bakurikiranwe imbonankubone na PBO nyuma y’umuhuza w’imyaka 22, barimo abarwayi 161 babazwe hakiri kare (mbere y’imyaka 46) (59%) n’abarwayi 113 wakoze inzira atinze (imyaka 46 kugeza 49) (41%).
Abitabiriye amahugurwa bagombaga kuba bafite imyaka 55 cyangwa irenga mugihe cyo kwiyandikisha kandi ntibatanzwe niba patologi yerekanaga ububi muri PBO yabo cyangwa niba bataragaragaye muri REP mumyaka 5 ishize.Bahuje imyaka nabitabiriye 240 mumatsinda yerekanwe badafite PBO.
Muri rusange, abagore bari bafite hagati yimyaka 67, bari 97% -99% byera, kandi hafi 60% ntabwo bigeze banywa itabi.
Indwara zidakira zapimwe n’ubuvuzi.Usibye amashyirahamwe yavuzwe haruguru, abashakashatsi ntibasanze hari isano iri hagati ya PBO na kanseri, diyabete, guta umutwe, hypertension, hyperlipidemia, umutima utera umutima, impyiko, tiroyide, cyangwa indwara y'umwijima, osteoporose, cyangwa igitero cy'igihe gito.
Isuzuma ry'umubiri ryarimo ingamba z'imbaraga no kugenda.Ugereranije n'itsinda ryerekanwe n'imyaka, abagore batewe na PBO bari bafite igipimo kinini cya tiroyide / pteronavicular kandi bakitwara nabi mugupimisha urugendo rw'iminota 6 (-14), mugihe abagore bakoze PBO kare bitwaye neza kuminota 6 ikizamini cyo kugenda (metero 18).Abagore bari mumatsinda ya nyuma ya PBO bari bafite igipimo kinini cyibinure byamavuta, umubyimba wa appendicular, hamwe nubucucike bwamagufwa yumugongo ugereranije nitsinda ryerekanwe.
Mielke na bagenzi be bavuze ko kubera ko ubushakashatsi bwambukiranya ibice, impamvu idashobora guterwa, kandi hasabwa ubushakashatsi bwigihe kirekire.Bavuze kandi ko abagore bitabiriye ubwo bushakashatsi bashobora kuba bafite ubuzima bwiza kurusha abaturage muri rusange kandi bagaragaza ko abazungu biganjemo ko ari imwe mu mbogamizi z’ubushakashatsi.
Hongguan yita kubuzima bwawe.
Reba ibicuruzwa byinshi bya Hongguan →https://www.hgcmedical.com/ibicuruzwa/
Niba hari ibikenewe mubuvuzi, nyamuneka twandikire.
hongguanmedical@outlook.com
Igihe cyo kohereza: Nzeri-18-2023